Find remote and flexible Machine Learning Engineer roles paying at least $100k in local currency. Filter by country, remote region, and salary band.
Browse $100k+ remote machine learning engineer roles from ATS feeds and trusted boards. We refresh daily and rank by salary first, so you see the strongest offers across regions.
ClickUp is seeking an experienced Machine Learning Engineer to join our Search team. You'll own the ML systems that power search relevance for millions of users and ground our AI in the right context.
Our customers increasingly need those same models on hardware we don't control: non-NVIDIA accelerators, edge servers, and embedded platforms with their own inference runtimes, operator sets, and constraints.
The AI/ML Engineering team builds and operates ClickHouse's AI and machine learning products end-to-end.
Own end-to-end machine learning initiatives from problem formulation and offline evaluation to production deployment and online A/B testing, driving measurable lifts in user engagement, retention, and trading activity.
Architect and deploy the multi-agent framework for agent assist, internal SOP execution, and secure LLM-powered actions, building scalable systems that handle millions of customer interactions.
Own the design and reliability of ML inference infrastructure serving both predictive models and LLMs, maintaining high availability and low latency at scale. Build and optimize low-latency streaming pipelines that deliver fresh, high-quality feature data to production ML models.
The Payments org at Airbnb is responsible for everything related to settling money in Airbnb’s global marketplace and makes the Payment experience as delightful, magical, intuitive, and easy as possible.
As a Machine Learning Engineer at Sardine, you'll own the systems that make real-time fraud detection possible. Our data science team builds custom models for our clients, you build and run the platform they deploy onto, and the low-latency serving path those models score on.
Getting a model from a research notebook to a production API serving millions of requests is one of the hardest problems in AI.
Our teams apply machine learning, optimization, and software engineering to solve complex problems for customers, shoppers, retailers, brands, and internal partners.
We are looking for a Senior Machine Learning Engineer with a strong Operations Research background to join the Service Availability & Routing team within Instacart's Logistics organization.
The Agentic AI team at Zillow is at the forefront of transforming the real estate industry by helping millions of people use AI assistants to find their next home.
The Agentic AI team at Zillow is at the forefront of transforming the real estate industry by helping millions of people use AI assistants to find their next home.
Design, build, and deploy machine learning models and systems that operate reliably at scale in production. Build and maintain ML infrastructure including feature stores, model serving platforms, and real-time inference pipelines.
We’re looking to hire a Senior Machine Learning Engineer to build models and data-driven systems that help classify, label, and enrich vast amounts of Internet data, providing direct value to customers and other parts of our organization.
How can we use vast amounts of proprietary and internet-scale healthcare data to build systems that enable access to significantly better health care?
71 of the 338 Machine Learning Engineer jobs on Six Figure Jobs (21%) can be done remotely, and every one publishes a salary of $100k+ or the local equivalent. Most of the remote openings are with employers based in United States, Canada and United Kingdom; some ask you to live in a given country or time zone, so check each listing.
Looking for hybrid or on-site roles as well? See all Machine Learning Engineer jobs.
Are these remote machine learning engineer jobs really $100k+?
Yes. We only include roles with validated high-salary compensation signals from company career pages and job boards.
How often do you refresh remote machine learning engineer jobs?
We refresh ATS sources daily, expire stale listings, and prioritize the newest high-paying openings.
Do you include hybrid/onsite machine learning engineer roles?
This page focuses on remote. For hybrid/onsite, use role pages or the work-arrangement filter in search.
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