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Python jobs paying $100k+ (779)

779 roles that list Python and pay $100k or more, with the salary shown on every listing and a link to the employer’s own application page.

Paragon Alpha - Hedge Fund Talent Business logo

Software/Data Engineer - Quant Hedge Fund - £250k+

Paragon Alpha - Hedge Fund Talent Business · 11d ago

£250k+London, UK
Spectrum IT Recruitment logo

Senior Python Developer - Cloud Automation

Spectrum IT RecruitmentNew · 21h ago

£100k+Southampton, UK
True Talent Solutions Partners logo

Member of Technical Staff, Applied Researcher

True Talent Solutions Partners · 10d ago

$300k - $500kNew York, USA
True Talent Solutions Partners logo

Senior Engineering Manager

True Talent Solutions Partners · 8d ago

$415k - $450kSan Francisco, USA
Hark logo
$180k - $450kSan Jose, USA
Hark logo
$180k - $450kSan Jose, USA
Hark logo
$180k - $450kSan Jose, USA
Pinterest logo
$285k - $450kUSA
Anthropic logo
C$320k - C$405kSan Francisco, CA +2
Mirendil logo
$300k - $400kSan Francisco, USA
True Talent Solutions Partners logo

Member of Technical Staff, Reinforcement Learning

True Talent Solutions Partners · 4d ago

$250k - $400k
Red Cell Partners logo
$250k - $400kUSA
Artificial Intelligence Underwriting Company logo

Member of Technical Staff - Engineering Lead

Artificial Intelligence Underwriting Company · 9d ago

$200k - $400kSan Francisco, USA
Plaid logo
$259k - $395kNew York City Office, USA
Stoke Space logo

Mission Design Lead

Stoke Space · 7d ago

$151k - $393kKent, USA
OpenAI logo
$347k - $385kSan Francisco, USA
OpenAI logo
$302k - $385kNew York City, USA
True Talent Solutions Partners logo

Principal Software Engineer, Perception

True Talent Solutions PartnersNew · 1d ago

$300k - $380kUSA
Nextdoor logo
$281k - $374kUSA
Roblox logo
$323k - $374kSan Mateo, USA
Pinterest logo
$177k - $365kUSA
Roblox logo
$329k - $362kSan Mateo, USA
True Talent Solutions Partners logo

Engineering Manager, AI Agents

True Talent Solutions PartnersNew · 12h ago

$300k - $360kNew York, USA
True Talent Solutions Partners logo

Engineering Manager, Agents

True Talent Solutions Partners · 9d ago

$300k - $360kNew York, USA
Superhuman logo

Director, Strategic Finance

Superhuman · 7d ago

$266k - $350kUSA
Preference Model logo
$200k - $350kSan Francisco, USA
Preference Model logo
$200k - $350kSan Francisco, USA
clearstreet logo
$200k - $350kChicago, USA
True Talent Solutions Partners logo

Member of Technical Staff, Applied ML

True Talent Solutions PartnersNew · 1d ago

$175k - $350kNew York, USA
Roblox logo
$279k - $345kSan Mateo, USA
Natera logo
$275k - $340kSan Carlos, USA
Snowflake logo
$236k - $339kUSA
Snowflake logo
$236k - $339kUSA
Jobgether logo
$128k - $339kUSA
Arm logo
$250k - $338kSan Diego, USA
Figma logo

Data Scientist

Figma · 1y ago

$136k - $338kSan Francisco, CA • New York, NY • United States
LILA Sciences logo
$252k - $336kUSA

Frequently asked questions

How much do Python jobs pay?
Python jobs on Six Figure Jobs all meet the $100k+ salary floor. Verified roles in this skill range from $75k to $500k based on current listings — seniority, team size, and remote eligibility all affect the final number.
Are there remote $100k+ Python jobs?
Yes. Many Python roles on Six Figure Jobs offer fully remote or hybrid arrangements. Each listing shows the work type and a direct apply link so you can quickly filter to distributed-friendly positions.
What other skills pair well with Python?
High-paying Python roles frequently appear alongside complementary technologies in cloud infrastructure, distributed systems, and data pipelines. Browse the full $100k+ Python job feed to see which skills co-occur most in current postings.