- Pays more than 97% of Senior Machine Learning Engineer jobs
- Degree required
- Apply on company site
- Benefits
- Relocation
Find remote and flexible Senior Machine Learning Engineer roles paying at least $100k in local currency. Filter by country, remote region, and salary band.
Browse $100k+ remote senior machine learning engineer roles from ATS feeds and trusted boards. We refresh daily and rank by salary first, so you see the strongest offers across regions.
This role sits at the intersection of ML workloads, execution systems, and engineering leverage.
As a Senior Software Engineer, ML Platform, you will work on our ML Data Team and be instrumental in architecting, implementing, and maintaining foundational ML infrastructure powering Feeds Ranking, Content Understanding, Recommendations, Ads, and much more to fulfill Reddit’s…
Build the machine learning capabilities that help advertisers understand what they could achieve on Reddit and make better investment decisions.
As a Senior ML Infrastructure Engineer, you will lead development of a platform for large scale ML models at Reddit.
Join the Ads team as a Machine Learning Engineer and become a key contributor to Reddit’s business. In this hands-on role, you will be responsible for the full lifecycle of our ML systems, from initial research and modeling to deployment and optimization in production.
Our partner is looking for a Senior Machine Learning Engineer, Inference based in the United States. Join a high-performing engineering team developing advanced real-time voice and large language model (LLM) technology.
Our Monetization team works on challenging problems every day.
We are looking for a Senior Machine Learning Engineer, Voice Experience to help build the next generation of AI-powered voice systems for the contact center.
Machine Learning Engineers at Cresta work across several high-impact AI initiatives. Final team placement is determined based on experience, strengths, and business needs.
Own end-to-end machine learning initiatives from problem formulation and offline evaluation to production deployment and online A/B testing, driving measurable lifts in user engagement, retention, and trading activity.
Architect and deploy the multi-agent framework for agent assist, internal SOP execution, and secure LLM-powered actions, building scalable systems that handle millions of customer interactions.
Own the design and reliability of ML inference infrastructure serving both predictive models and LLMs, maintaining high availability and low latency at scale. Build and optimize low-latency streaming pipelines that deliver fresh, high-quality feature data to production ML models.
The Payments org at Airbnb is responsible for everything related to settling money in Airbnb’s global marketplace and makes the Payment experience as delightful, magical, intuitive, and easy as possible.
Our teams apply machine learning, optimization, and software engineering to solve complex problems for customers, shoppers, retailers, brands, and internal partners.
We are looking for a Senior Machine Learning Engineer with a strong Operations Research background to join the Service Availability & Routing team within Instacart's Logistics organization.
On the ML Fraud team, you’ll build and improve machine learning systems that make real-time transaction decisions, protecting consumers and merchants while balancing fraud loss, customer experience, and conversion.
Design, build, and deploy machine learning models and systems that operate reliably at scale in production. Build and maintain ML infrastructure including feature stores, model serving platforms, and real-time inference pipelines.
We’re looking to hire a Senior Machine Learning Engineer to build models and data-driven systems that help classify, label, and enrich vast amounts of Internet data, providing direct value to customers and other parts of our organization.
Our teams apply machine learning, optimization, and software engineering to solve complex problems for customers, shoppers, retailers, brands, and internal partners.
23 of the 110 Senior Machine Learning Engineer jobs on Six Figure Jobs (21%) can be done remotely, and every one publishes a salary of $100k+ or the local equivalent. Most of the remote openings are with employers based in United States and Canada; some ask you to live in a given country or time zone, so check each listing.
Looking for hybrid or on-site roles as well? See all Senior Machine Learning Engineer jobs.
Are these remote senior machine learning engineer jobs really $100k+?
Yes. We only include roles with validated high-salary compensation signals from company career pages and job boards.
How often do you refresh remote senior machine learning engineer jobs?
We refresh ATS sources daily, expire stale listings, and prioritize the newest high-paying openings.
Do you include hybrid/onsite senior machine learning engineer roles?
This page focuses on remote. For hybrid/onsite, use role pages or the work-arrangement filter in search.